Main page (Russian) Search in database (English)

Properties of substance:

EA 3940



skc-file

Synonyms:

palytoxin

Group of substances:

organic

Physical appearance:

colorless amorphous substance

Empirical formula (Hill's system for organic substances):

C129H223N3O54

Molar/atomic mass: 2680.14

Decomposition temperature (°C):

300

CAS №: 11077-03-5

Solubility (g/100 g of solvent):

acetone: insoluble [Ref.]
chloroform: insoluble [Ref.]
diethyl ether: insoluble [Ref.]
dimethylsulfoxide: soluble [Ref.]
ethanol: slightly soluble [Ref.]
pyridine: soluble [Ref.]
water: soluble [Ref.]

Hygroscopic:

yes

LD50 (mg/kg):

0.0002 (cats, )
0.000025 (rabbits, intravenous)
0.04 (rats, oral)
0.01 (rats, rectal)
0.000089 (rats, intravenous)
0.0004 (rats, subcutaneous)
0.00036 (rats, intratracheal)
0.00024 (rats, intramuscular)
0.00063 (rats, intraperitoneal)
0.00011 (guinea pig, intravenous)
0.00045 (mice, intravenous)
1.27 (mice, onto the skin)
0.00015 (mice, intraperitoneal)
0.000078 (monkeys, intravenous)
0.000033 (dogs, intravenous)

References:

  1. Blunt J.W., Munro M.H.G. Dictionary of marine Natural Products. - Chapman and Hall/CRC, 2008. - pp. 1527
  2. Botana L.M. Phycotoxins. Chemistry and Biochemistry. - Blackwell Publishing, 2007. - pp. 75-82, 95-104
  3. Botana L.M. Seafood and freshwater toxins: Pharmacology, Physiology and Detection. - 2ed. - 2008. - pp. 633
  4. Journal of Toxicology - Toxin Reviews. - 1987. - Vol. 6, №2. - pp. 159-187
  5. Lewis R.J. Sax's Dangerous Properties of Industrial Materials. - 12ed., Vol. 1-5. - Wiley, 2012. - pp. 3466
  6. Marine Drugs. - 2010. - vol.8, №7. - pp. 2021-2037
  7. Potential military chemical/biological agents and compounds. - Washington: Departament of the Army, 1990. - pp. 83
  8. Rappuoli R., Montecucco C. Guidebook to protein toxins and their use in cell biology. - 1997. - pp. 239-241
  9. Антонов Н.С. Химическое оружие на рубеже двух столетий. - М., 1994. - pp. 117-121 [Russian]
  10. Успехи химии. - 2010. - Т.79, №5. - pp. 446 [Russian]
  11. Химическая энциклопедия. - Т. 5. - М.: Советская энциклопедия, 1999. - pp. 525-527 [Russian]

    What information do you need?




    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru