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Properties of substance:
naproxen
skc-file
Group of substances:
organic
Physical appearance:
crystals
Empirical formula (Hill's system for organic substances):
C
1
4
H
1
4
O
3
Structural formula as text:
CH3OC10H6CH(CH3)COOH
Molar/atomic mass: 230.259
Melting point (°C):
155
CAS №: 22204-53-1
Solubility (g/100 g of solvent):
1,4-dioxane
: 32.2 (25°C) [
Ref.
]
1-butanol
: 4.73 (25°C) [
Ref.
]
chloroform
: soluble [
Ref.
]
diethyl ether
: sparingly soluble [
Ref.
]
methanol
: soluble [
Ref.
]
water
: 0.0009924 (5°C) [
Ref.
]
water
: 0.00159 (25°C) [
Ref.
]
LD
50
(mg/kg):
248 (rats, oral)
360 (mice, oral)
435 (mice, intravenous)
References:
CRC Handbook of Chemistry and Physics. - 90ed. - CRC Press, 2010. - pp. 3-386
Jouyban A. Handbook of solubility data for pharmaceutacals. – CRC Press, 2010. - pp. 75
Kleemann A. Pharmaceutical Substances. - 2000. - pp. 1399-1403
The Merck Index 11th ed., Merck & Company, 1989. - pp. 1014
Химический энциклопедический словарь. - Под ред. Кнунянц И.Л. - М.: Советская энциклопедия, 1983. - pp. 359 [Russian]
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© Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru