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Properties of substance:

naproxen



skc-file

Group of substances:

organic

Physical appearance:

crystals

Empirical formula (Hill's system for organic substances):

C14H14O3

Structural formula as text:

CH3OC10H6CH(CH3)COOH

Molar/atomic mass: 230.259

Melting point (°C):

155

CAS №: 22204-53-1

Solubility (g/100 g of solvent):

1,4-dioxane: 32.2 (25°C) [Ref.]
1-butanol: 4.73 (25°C) [Ref.]
chloroform: soluble [Ref.]
diethyl ether: sparingly soluble [Ref.]
methanol: soluble [Ref.]
water: 0.0009924 (5°C) [Ref.]
water: 0.00159 (25°C) [Ref.]

LD50 (mg/kg):

248 (rats, oral)
360 (mice, oral)
435 (mice, intravenous)

References:

  1. CRC Handbook of Chemistry and Physics. - 90ed. - CRC Press, 2010. - pp. 3-386
  2. Jouyban A. Handbook of solubility data for pharmaceutacals. – CRC Press, 2010. - pp. 75
  3. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 1399-1403
  4. The Merck Index 11th ed., Merck & Company, 1989. - pp. 1014
  5. Химический энциклопедический словарь. - Под ред. Кнунянц И.Л. - М.: Советская энциклопедия, 1983. - pp. 359 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru