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Properties of substance:

dextromoramide

Group of substances:

organic

Empirical formula (Hill's system for organic substances):

C25H32N2O2

Structural formula as text:

O(CH2CH2)2NCH2CH(CH3)C(C6H5)2CON(CH2)4

Molar/atomic mass: 392.55

Melting point (°C):

183-184

CAS ¹: 357-56-2

Solubility (g/100 g of solvent):

acetone: 63.3 (20°C) [Ref.]
benzene: 5.7 (20°C) [Ref.]
chloroform: 3.4 (20°C) [Ref.]
ethanol: 64 (20°C) [Ref.]
ethyl acetate: 44.4 (20°C) [Ref.]
methanol: 50.6 (20°C) [Ref.]
water: practically insoluble [Ref.]

Retention indices for gas chromatography:

2940 (phase - SE-30)

LD50 (mg/kg):

71.8 (rats, oral)
13 (rats, intravenous)
168 (mice, oral)
21 (mice, intravenous)

References:

  1. Buschmann H., Christoph T., Friderichs E., Maul C., Sundermann B. Analgesics from Chemistry and Pharmacology to Clinical Application. - 2002. - pp. 181-182
  2. Clarke's Analysis of Drugs and Poisons. - 4 ed. - London, 2011. - pp. 1219-1220
  3. Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 521-522
  4. Elks J., Ganellin C.R. Dictionary of Drugs: Chemical Data, Structures and Bibliographies. - Springer, 1990. - pp. 837
  5. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 616-617
  6. The Merck Index 11th ed., Merck & Company, 1989. - pp. 466

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru