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Properties of substance:

digoxin



skc-file

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C41H64O14

Molar/atomic mass: 780.94

Melting point (°C):

265

Decomposition temperature (°C):

265

CAS №: 20830-75-5

Solubility (g/100 g of solvent):

acetone: practically insoluble [Ref.]
chloroform: sparingly soluble [Ref.]
diethyl ether: practically insoluble [Ref.]
ethanol: practically insoluble [Ref.]
ethanol 80%: 0.82 (20°C) [Ref.]
ethyl acetate: practically insoluble [Ref.]
pyridine: 25 (20°C) [Ref.]
water: 0.0098 (25°C) [Ref.]

LD50 (mg/kg):

0.2 (cats, oral)
3.5 (guinea pig, oral)
7.67 (mice, intravenous)
0.075 (mens, oral)

References:

  1. Clarke's Analysis of Drugs and Poisons. - 4 ed. - London, 2011. - pp. 1251-1252
  2. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 645-646
  3. Rocnik. - 2008. - LXXVII, №4. - pp. 162
  4. Yalkowsky S.H., Yan H., Jain P. Handbook of aqueous solubility data. – 2nd ed. - CRC Press, 2010. - pp. 1346
  5. Полюдек-Фабини Р., Бейрих Т. Органический анализ. - Л.: Химия, 1981. - pp. 443 [Russian]
  6. Регистр лекарственных средств России: Энциклопедия лекарств. - 8 изд. - М., 2001. - pp. 284 [Russian]
  7. Хейфиц Л.А., Дашунин В.М. Душистые вещества и другие продукты для парфюмерии. - М.: Химия, 1994. - pp. 206 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru