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Properties of substance:

4-aminophenol

Synonyms:

p-aminophenol

Group of substances:

organic

Physical appearance:

colorless leaflets crystals

Empirical formula (Hill's system for organic substances):

C6H7NO

Structural formula as text:

H2NC6H4OH

Molar/atomic mass: 109.1259

Melting point (°C):

184

Decomposition temperature (°C):

184

Solubility (g/100 g of solvent):

benzene: insoluble [Ref.]
chloroform: insoluble [Ref.]
diethyl ether: difficulty soluble [Ref.]
ethanol: 5.7 (0°C) [Ref.]
methyl ethyl ketone: 9.3 (58°C) [Ref.]
water: 1.1 (0°C) [Ref.]
water: 1.283 (10°C) [Ref.]
water: 1.575 (20°C) [Ref.]
water: 1.865 (30°C) [Ref.]
water: 2.248 (40°C) [Ref.]
water: 3.475 (60°C) [Ref.]
water: 7.322 (80°C) [Ref.]
water: 27.01 (100°C) [Ref.]

Dissociation:

pKBH+ (1) = 5.48 (25°C, water)
pKa (1) = 10.3 (25°C, water)

LD50 (mg/kg):

375 (rats, oral)
420 (mice, oral)

References:

  1. CRC Handbook of Chemistry and Physics. - 95ed. - CRC Press, 2014. - pp. 3-24
  2. Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 342-343
  3. Lewis R.J. Sax's Dangerous Properties of Industrial Materials. - 11ed. - Wiley-interscience, 2004. - pp. 207-208
  4. Milne G.W.A. Gardner's Commercially Important Chemicals. - Wiley-Interscience, 2005. - pp. 29
  5. Seidell A. Solubilities of organic compounds. - 3ed., vol.2. - New York: D. Van Nostrand Company, 1941. - pp. 421-422
  6. Yalkowsky S.H., Yan H. Handbook of aqueous solubility data. - CRC Press, 2003. - pp. 263
  7. Справочник по растворимости. - Т.1, Кн.1. - М.-Л.: ИАН СССР, 1961. - pp. 444 [Russian]
  8. Справочник химика. - Т. 2. - Л.-М.: Химия, 1964. - pp. 1042-1043 [Russian]
  9. Химическая энциклопедия. - Т. 1. - М.: Советская энциклопедия, 1988. - pp. 146 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru