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Properties of substance:
procaine hydrochloride
Group of substances:
organic
Physical appearance:
colorless needles crystals
Empirical formula (Hill's system for organic substances):
C
1
3
H
2
1
ClN
2
O
2
Structural formula as text:
H2NC6H4COOCH2CH2N(C2H5)2 * HCl
Molar/atomic mass: 272.77
Melting point (°C):
155
CAS №: 51-05-8
Solubility (g/100 g of solvent):
chloroform
: sparingly soluble [
Ref.
]
diethyl ether
: practically insoluble [
Ref.
]
ethanol
: 3 (20°C) [
Ref.
]
water
: 100 (20°C) [
Ref.
]
Density:
0.707 (17°C, g/cm
3
)
LD
50
(mg/kg):
200 (rats, oral)
38 (rats, intravenous)
175 (mice, oral)
33 (mice, intravenous)
63 (dogs, intravenous)
References:
Elks J., Ganellin C.R. Dictionary of Drugs: Chemical Data, Structures and Bibliographies. - Springer, 1990. - pp. 1020
Kleemann A. Pharmaceutical Substances. - 2000. - pp. 1711-1712
Seidell A. Solubilities of organic compounds. - 3ed., vol.2. - New York: D. Van Nostrand Company, 1941. - pp. 729
The Merck Index 11th ed., Merck & Company, 1989. - pp. 1231
Беликов В.Г. Учебное пособие по фармацевтической химии. - М.: Медицина, 1979. - pp. 211 [Russian]
Справочник химика. - Т. 2. - Л.-М.: Химия, 1964. - pp. 898-899 [Russian]
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© Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru