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Properties of substance:

chloropropamide

Synonyms:

4-chloro-N-[(propylamino)carbonyl]benzenesulfonamide

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C10H13ClN2O3S

Structural formula as text:

ClC6H4SO2NHCONHCH2CH2CH3

Molar/atomic mass: 276.74

Melting point (°C):

128

Solubility (g/100 g of solvent):

acetone: soluble [Ref.]
benzene: sparingly soluble [Ref.]
chloroform: soluble [Ref.]
diethyl ether: sparingly soluble [Ref.]
ethanol: soluble [Ref.]
water: 0.08913 (25°C) [Ref.]

LD50 (mg/kg):

2655.5 (, oral)
1701.5 (, oral)
409.3 (, intraperitoneal)

References:

  1. CRC Handbook of Chemistry and Physics. - 95ed. - CRC Press, 2014. - pp. 3-118
  2. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 446-447
  3. Yalkowsky S.H., Yan H., Jain P. Handbook of aqueous solubility data. – 2nd ed. - CRC Press, 2010. - pp. 692
  4. Беликов В.Г. Учебное пособие по фармацевтической химии. - М.: Медицина, 1979. - pp. 191-192 [Russian]
  5. Токсикологический вестник. - 1995. - №3. - pp. 36 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru