Main page (Russian) Search in database (English)

Properties of substance:

N-[(butylamino)carbonyl]-4-methylbenzenesulfonamide

Synonyms:

tolbutamide

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C12H18N2O3S

Structural formula as text:

CH3C6H4SO2NHCONHCH2CH2CH2CH3

Molar/atomic mass: 270.35

Melting point (°C):

128

Solubility (g/100 g of solvent):

acetone: very soluble [Ref.]
chloroform: very soluble [Ref.]
diethyl ether: sparingly soluble [Ref.]
ethanol: soluble [Ref.]
water: 0.014 (25°C) [Ref.]

LD50 (mg/kg):

8037.8 (, oral)
2883 (mice, oral)

References:

  1. CRC Handbook of Chemistry and Physics. - 90ed. - CRC Press, 2010. - pp. 3-486
  2. Yalkowsky S.H., Yan H., Jain P. Handbook of aqueous solubility data. – 2nd ed. - CRC Press, 2010. - pp. 906
  3. Беликов В.Г. Учебное пособие по фармацевтической химии. - М.: Медицина, 1979. - pp. 191-192 [Russian]
  4. Краткая химическая энциклопедия. - Т. 3: Мальтаза-Пиролиз. - М.: Советская энциклопедия, 1964. - pp. 358 [Russian]
  5. Токсикологический вестник. - 1995. - №2. - pp. 36 [Russian]

    What information do you need?




    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru