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Properties of substance:

reserpine



skc-file

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C33H40N2O9

Molar/atomic mass: 608.6787

Melting point (°C):

261-265

CAS №: 50-55-5

Solubility (g/100 g of solvent):

acetic acid: very soluble [Ref.]
chloroform: very soluble [Ref.]
ethanol: very slightly soluble [Ref.]
water: 0.0073 (30°C) [Ref.]

Dissociation:

pKBH+ (1) = 6.6 (25°C, water)

LD50 (mg/kg):

420 (rats, oral)
15 (rats, intravenous)
200 (mice, oral)
21 (mice, intravenous)
0.5 (dogs, intravenous)

References:

  1. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 1801-1802
  2. Yalkowsky S.H., Yan H. Handbook of aqueous solubility data. - CRC Press, 2003. - pp. 1251
  3. Беликов В.Г. Учебное пособие по фармацевтической химии. - М.: Медицина, 1979. - pp. 389 [Russian]
  4. Муравьева Д.А. Тропические и субтропические лекарственные растения. - М.: Медицина, 1983. - pp. 196-200 [Russian]
  5. Химическая энциклопедия. - Т. 4. - М.: Советская энциклопедия, 1995. - pp. 224 [Russian]
  6. Химический энциклопедический словарь. - Под ред. Кнунянц И.Л. - М.: Советская энциклопедия, 1983. - pp. 502 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru