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Properties of substance:
convallatoxin
skc-file
Group of substances:
organic
Physical appearance:
white prismatic crystals
Empirical formula (Hill's system for organic substances):
C
2
9
H
4
2
O
1
0
Molar/atomic mass: 550.638
Melting point (°C):
212
Solubility (g/100 g of solvent):
acetone
: soluble [
Ref.
]
chloroform
: difficulty soluble [
Ref.
]
diethyl ether
: practically insoluble [
Ref.
]
ethanol
: soluble [
Ref.
]
ethyl acetate
: difficulty soluble [
Ref.
]
petroleum ether: practically insoluble [
Ref.
]
water
: 0.05 (20°C) [
Ref.
]
LD
50
(mg/kg):
3.65 (cats, oral)
0.18 (cats, intraperitoneal)
0.185 (guinea pig, intravenous)
0.2 (guinea pig, intraperitoneal)
1 (mice, intravenous)
10 (mice, intraperitoneal)
0.09 (monkeys, intravenous)
References:
Kleemann A. Pharmaceutical Substances. - 2000. - pp. 544-545
Rocnik. - 2008. - LXXVII, №4. - pp. 162
The Merck Index 11th ed., Merck & Company, 1989. - pp. 392
Беликов В.Г. Учебное пособие по фармацевтической химии. - М.: Медицина, 1979. - pp. 417 [Russian]
Полюдек-Фабини Р., Бейрих Т. Органический анализ. - Л.: Химия, 1981. - pp. 445 [Russian]
Химический энциклопедический словарь. - Под ред. Кнунянц И.Л. - М.: Советская энциклопедия, 1983. - pp. 271 [Russian]
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© Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru