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Properties of substance:
metamizol
skc-file
Synonyms:
dipyrone
Group of substances:
organic
Physical appearance:
colorless needles crystals
Empirical formula (Hill's system for organic substances):
C
1
3
H
1
8
N
3
NaO
5
S
Molar/atomic mass: 351.36
Melting point (°C):
172
CAS №: 5907-38-0
Solubility (g/100 g of solvent):
acetone
: practically insoluble [
Ref.
]
chloroform
: practically insoluble [
Ref.
]
diethyl ether
: insoluble [
Ref.
]
ethanol
: 3.3 (20°C) [
Ref.
]
water
: 66.7 (20°C) [
Ref.
]
LD
50
(mg/kg):
3300 (white mice, oral)
References:
Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 563-564
Kleemann A. Pharmaceutical Substances. - 2000. - pp. 1270-1271
Беликов В.Г. Учебное пособие по фармацевтической химии. - М.: Медицина, 1979. - pp. 257 [Russian]
Справочник химика. - Т. 2. - Л.-М.: Химия, 1964. - pp. 420-421 [Russian]
Халецкий А.М. Фармацевтическая химия. - Л.: Медицина, 1966. - pp. 333-334 [Russian]
Химический энциклопедический словарь. - Под ред. Кнунянц И.Л. - М.: Советская энциклопедия, 1983. - pp. 46 [Russian]
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© Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru