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Properties of substance:

lidocaine

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C14H25ClN2O2

Structural formula as text:

(CH3)2C6H3NHCOCH2N(C2H5)2HCl * H2O

Molar/atomic mass: 288.814

Melting point (°C):

77-78

Solubility (g/100 g of solvent):

chloroform: soluble [Ref.]
diethyl ether: insoluble [Ref.]
ethanol: soluble [Ref.]
water: very soluble [Ref.]

LD50 (mg/kg):

21 (rats, intravenous)
220 (mice, oral)
15 (mice, intravenous)

References:

  1. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 1173-1174
  2. The Merck Index 11th ed., Merck & Company, 1989. - pp. 863
  3. Беликов В.Г. Учебное пособие по фармацевтической химии. - М.: Медицина, 1979. - pp. 185 [Russian]
  4. Машковский М.Д. Лекарственные средства. - 13-е изд., Т. 1. - Харьков: Торсинг, 1997. - pp. 299 [Russian]
  5. Полюдек-Фабини Р., Бейрих Т. Органический анализ. - Л.: Химия, 1981. - pp. 291 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru