Main page (Russian) Search in database (English)

Properties of substance:

berberine



skc-file

Group of substances:

organic

Physical appearance:

crystals

Empirical formula (Hill's system for organic substances):

C20H19NO5

Molar/atomic mass: 353.369

Melting point (°C):

144

CAS №: 2086-83-1

Solubility (g/100 g of solvent):

benzene: difficulty soluble [Ref.]
chloroform: difficulty soluble [Ref.]
diethyl ether: difficulty soluble [Ref.]
ethanol: difficulty soluble [Ref.]
water: 22 (21°C) [Ref.]

Dissociation:

pKBH+ (1) = 11.73 (25°C, water)

LD50 (mg/kg):

9.55 (white mice, intravenous)
205 (rats, intraperitoneal)
57 (mice, intraperitoneal)

References:

  1. CRC Handbook of Chemistry and Physics. - 95ed. - CRC Press, 2014. - pp. 3-46
  2. Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 391-392
  3. Dean J.A. Lange's handbook of chemistry. - 1999. - pp. 8.31
  4. Lewis R.J. Sax's Dangerous Properties of Industrial Materials. - 11ed. - Wiley-interscience, 2004. - pp. 418
  5. Ramawat K.G., Merillon J.-M. Natural Products. Phytochemistry, Botany and Metabolism of Alkaloids, Phenolic and Terpenes. - Springer, 2013. - pp. 1319
  6. Каррер П. Курс органической химии. - 2-е изд., под ред. Колосова М.Н. - Л.: ГНТИХЛ, 1962. - pp. 1102-1104 [Russian]
  7. Муравьева Д.А. Фармакогнозия (с основами биохимии лекарственных растений). - М.: Медицина, 1978. - pp. 358 [Russian]
  8. Потопальский А.И. Препараты чистотела в биологии и медицине. - Киев: Наукова думка, 1992. - pp. 21-26 [Russian]
  9. Справочник химика. - Т. 2. - Л.-М.: Химия, 1964. - pp. 534-535 [Russian]
  10. Химическая энциклопедия. - Т. 1. - М.: Советская энциклопедия, 1988. - pp. 279 [Russian]

    What information do you need?




    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru