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Properties of substance:
5-(2-chlorophenyl)-7-nitro-1,3-dihydro-1,4-benzodiazepin-2-on
skc-file
Synonyms:
clonazepam
Group of substances:
organic
Physical appearance:
white crystals
Empirical formula (Hill's system for organic substances):
C
1
5
H
1
0
ClN
3
O
3
Molar/atomic mass: 315.712
Melting point (°C):
236.5-238.5
CAS ¹: 1622-61-3
Solubility (g/100 g of solvent):
1-butanol
: 0.33 (25°C) [
Ref.
]
1-pentanol
: 0.28 (25°C) [
Ref.
]
2-phenylethanol
: 2.39 (25°C) [
Ref.
]
N-methylpyrrolidone
: 20.5 (25°C) [
Ref.
]
acetone
: 3.9 (25°C) [
Ref.
]
benzene
: 0.06 (25°C) [
Ref.
]
benzylic alcohol
: 3.22 (25°C) [
Ref.
]
chloroform
: 1 (25°C) [
Ref.
]
diethyl ether
: 0.1 (25°C) [
Ref.
]
ethanol
: 0.65 (25°C) [
Ref.
]
methanol
: 1.1 (25°C) [
Ref.
]
water
: 0.003 (25°C) [
Ref.
]
References:
Clarke's Analysis of Drugs and Poisons. - 4 ed. - London, 2011. - pp. 1136-1138
Jouyban A. Handbook of solubility data for pharmaceutacals. – CRC Press, 2010. - pp. 74, 86, 117, 192, 301-303
The Merck Index 11th ed., Merck & Company, 1989. - pp. 373-374
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© Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru