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Properties of substance:

ketamine hydrochloride



skc-file

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C13H17Cl2NO

Molar/atomic mass: 274.19

Melting point (°C):

258-261

CAS №: 1867-66-9

Solubility (g/100 g of solvent):

chloroform: soluble [Ref.]
ethanol: very soluble [Ref.]
methanol: very soluble [Ref.]
water: 20 (20°C) [Ref.]

Dissociation:

pKBH+ (1) = 7.5 (25°C, water)

LD50 (mg/kg):

59 (rats, intravenous)
224 (rats, intraperitoneal)

References:

  1. Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 694
  2. The Merck Index 11th ed., Merck & Company, 1989. - pp. 834
  3. Бабаян Э.А., Гаевский А.В., Бардин Е.В. Правовые аспекты оборота наркотических, психотропных, сильнодействующих, ядовитых веществ и прекурсоров. - М.: МЦФЭР, 2000. - pp. 146 [Russian]
  4. Государственная Фармакопея Российской Федерации. - 12 изд., ч. 1 - М.: НЦЭСМП, 2008. - pp. 557-558 [Russian]
  5. Кудрин А.Н., Воробьев В.Г. Аминокетоны. - М.: Медицина, 1970. - pp. 266-267 [Russian]
  6. Регистр лекарственных средств России: Энциклопедия лекарств. - 8 изд. - М., 2001. - pp. 405-406 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru