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Properties of substance:
tetrodotoxin
skc-file
Group of substances:
organic
Physical appearance:
colorless crystals
Empirical formula (Hill's system for organic substances):
C
1
3
H
2
1
N
3
O
1
0
Molar/atomic mass: 379.32
Melting point (°C):
225
Decomposition temperature (°C):
225
Solubility (g/100 g of solvent):
diethyl ether
: soluble [
Ref.
]
ethanol
: soluble [
Ref.
]
water
: slightly soluble [
Ref.
]
Dissociation:
pK
BH
+
(1) = 8.7 (20°C, water)
LD
50
(mg/kg):
0.008 (white mice, intramuscular)
0.008 (mice, intraperitoneal)
0.01 (mens, oral)
References:
Angewandte Chemie International Edition. - 2004. - Vol. 43, No. 36. - pp. 4782-4785
Journal of the American Chemical Society. - 2003. - vol. 125, No. 29. - pp. 8798-8805
Journal of the American Chemical Society. - 2003. - vol. 125, No. 38. - pp. 11510-11511
Marine Drugs. - 2011. - vol.9, №10. - pp. 2046-2074
Marine Drugs. - 2012. - vol.10, №2. - pp. 281-305
Досон Р., Эллиот Д., Эллиот У., Джонс К. Справочник биохимика. - М.: Мир, 1991. - pp. 244 [Russian]
Морской флот. - 1983. - №4. - pp. 36-37 [Russian]
Неотложная помощь при острых отравлениях: Справочник по токсикологии. - Под ред. Голикова С.Н. - М.: Медицина, 1977. - pp. 236 [Russian]
Химическая энциклопедия. - Т. 5. - М.: Советская энциклопедия, 1999. - pp. 526 [Russian]
Химический энциклопедический словарь. - Под ред. Кнунянц И.Л. - М.: Советская энциклопедия, 1983. - pp. 727 [Russian]
Хухо Ф. Нейрохимия: Основы и принципы. - М.: Мир, 1990. - pp. 146 [Russian]
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© Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru