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Properties of substance:
benzeneboronic acid
Synonyms:
phenylboronic acid
Group of substances:
elmentoorganic
Empirical formula (Hill's system for organic substances):
C6H7BO2Structural formula as text:
C6H5B(OH)2Molar/atomic mass: 121.94
Decomposition temperature (°C):
110Solubility (g/100 g of solvent):
benzene: 1.75 (25°C) [Ref.]
diethyl ether: 30.2 (25°C) [Ref.]
ethanol: soluble [Ref.]
methanol: 178 (25°C) [Ref.]
water: 2.5 (25°C) [Ref.]
xylene: 1.2 (25°C) [Ref.]
Synthesis 1:
Reference: A Textbook of inorganic chemistry. Organometallic compounds. - vol.XI, part 1. - London, 1928 pp. 229The magnesium compound from 50 grams of bromobenzene in 200 c.c. of ether is saturated with the boron trifluoride from 52 grams of potassium borofluoride, 8 grams of boron trioxide, and 100 c.c. of concentrated sulphuric acid. After boiling for two hours under reflux, the product is ice cooled, and decomposed by cautiously adding 60 c.c. of water. The ether layer is then separated off, and the residue extracted several times with ether, the solvent removed, and the solid obtained boiled with 100 c.c. of water for one hour on the water-bath and filtered whilst hot. On slowly cooling, pure phenyl boric acid separates in snow-white bushy needles, several centimeters in length, M.pt. 216°C.
Dissociation:
pKa (1) = 8.9 (°C, water)
Standard molar enthalpy (heat) of formation ΔfH0 (298.15 K, kJ/mol):
-719.6 (s)LD50 (mg/kg):
740 (rats, oral)
320 (mice, intravenous)
500 (mice, intraperitoneal)
References:
- Armarego W. L. F. Purification of Laboratory Chemicals. - 7ed. - 2013. - pp. 521
- Dictionary of organic compounds. - Vol.4: Obaculactone-Zymosterol. - New York, 1953. - pp. 107-108
- Hall D.G. Boronic Acids, 2005. - pp. 10
- Lewis R.J. Sax's Dangerous Properties of Industrial Materials. - 11ed. - Wiley-interscience, 2004. - pp. 361
- Кочешков К.А., Несмеянов А.Н. Синтетические методы в области металлорганических соединений элементов 3 группы. - М.-Л.: ИАН СССР, 1945. - pp. 42 [Russian]
- Краткая химическая энциклопедия. - Т. 1: А-Е. - М.: Советская энциклопедия, 1961. - pp. 461 [Russian]
- Справочник химика. - Т. 2. - Л.-М.: Химия, 1964. - pp. 538-539 [Russian]
- Справочник химика. - Т. 3. - М.-Л.: Химия, 1965. - pp. 95 [Russian]
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© Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru