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Properties of substance:
benactyzine hydrochloride
Synonyms:
EA 2092
parasan
benacyzine
tranquilline
Group of substances:
organic
Physical appearance:
white crystals
Empirical formula (Hill's system for organic substances):
C
2
0
H
2
6
ClNO
3
Structural formula as text:
(C6H5)2C(OH)COOCH2CH2N(C2H5)2 * HCl
Molar/atomic mass: 363.88
Melting point (°C):
177-179
Solubility (g/100 g of solvent):
diethyl ether
: practically insoluble [
Ref.
]
ethanol
: difficulty soluble [
Ref.
]
water
: 14.9 (25°C) [
Ref.
]
LD
50
(mg/kg):
184 (rats, oral)
160 (mice, oral)
14.3 (mice, intravenous)
References:
Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 375
Kleemann A. Pharmaceutical Substances. - 2000. - pp. 188
Lewis R.J. Sax's Dangerous Properties of Industrial Materials. - 11ed. - Wiley-interscience, 2004. - pp. 371-372
The Merck Index 11th ed., Merck & Company, 1989. - pp. 160
Машковский М.Д. Лекарственные средства. - 13-е изд., Т. 1. - Харьков: Торсинг, 1997. - pp. 80-81 [Russian]
Химический энциклопедический словарь. - Под ред. Кнунянц И.Л. - М.: Советская энциклопедия, 1983. - pp. 33 [Russian]
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© Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru