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Properties of substance:
N-(4-nitro-2-phenoxyphenyl)methanesulfonamide
Synonyms:
nimesulide
Group of substances:
organic
Empirical formula (Hill's system for organic substances):
C
1
3
H
1
2
N
2
O
5
S
Molar/atomic mass: 308.05
Melting point (°C):
143-144.5
CAS ¹: 51803-78-2
Solubility (g/100 g of solvent):
1-butanol
: 0.26 (25°C) [
Ref.
]
water
: 0.0014 (25°C) [
Ref.
]
water
: 0.00228 (37°C) [
Ref.
]
LD
50
(mg/kg):
200 (rats, oral)
392 (mice, oral)
References:
Buschmann H., Christoph T., Friderichs E., Maul C., Sundermann B. Analgesics from Chemistry and Pharmacology to Clinical Application. - 2002. - pp. 90
Jouyban A. Handbook of solubility data for pharmaceutacals. – CRC Press, 2010. - pp. 75
Kleemann A. Pharmaceutical Substances. - 2000. - pp. 1443-1444
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© Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru