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Properties of substance:
l-aspartic acid
Group of substances:
organic
Empirical formula (Hill's system for organic substances):
C
4
H
7
NO
4
Structural formula as text:
HOOCCH2CH(NH2)COOH
Molar/atomic mass: 133.103
Melting point (°C):
270
Solubility (g/100 g of solvent):
diethyl ether
: insoluble [
Ref.
]
ethanol
: insoluble [
Ref.
]
water
: 0.223 (0°C) [
Ref.
]
water
: 0.422 (20°C) [
Ref.
]
water
: 0.5018 (25°C) [
Ref.
]
water
: 0.845 (40°C) [
Ref.
]
water
: 1.238 (50°C) [
Ref.
]
water
: 2.642 (75°C) [
Ref.
]
Dissociation:
pK
a
(1) = 3.9 (25°C, water)
pK
a
(2) = 10 (25°C, water)
Standard molar enthalpy (heat) of formation Δ
f
H
0
(298.15 K, kJ/mol):
-973.3 (s)
LD
50
(mg/kg):
6000 (mice, intraperitoneal)
References:
CRC Handbook of Chemistry and Physics. - 90ed. - CRC Press, 2010. - pp. 5-26
Journal of Chemical Thermodynamics. - 2008. - Vol. 40, No. 5. - pp. 897-900
Kleemann A. Pharmaceutical Substances. - 2000. - pp. 140-141
Lewis R.J. Sax's Dangerous Properties of Industrial Materials. - 11ed. - Wiley-interscience, 2004. - pp. 311
Seidell A. Solubilities of organic compounds. - 3ed., vol.2. - New York: D. Van Nostrand Company, 1941. - pp. 239-240
Yalkowsky S.H., Yan H., Jain P. Handbook of aqueous solubility data. – 2nd ed. - CRC Press, 2010. - pp. 106-107
Губен И. Методы органической химии. - Т. 4, Вып. 2. - М.-Л.: ГНТИХЛ, 1949. - pp. 910 [Russian]
Справочник по растворимости. - Т.1, Кн.1. - М.-Л.: ИАН СССР, 1961. - pp. 396 [Russian]
Справочник химика. - Т. 2. - Л.-М.: Химия, 1964. - pp. 448-449 [Russian]
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© Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru