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Properties of substance:

carbamazepine



skc-file

Synonyms:

temporal
finlepsin

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C15H12N2O

Molar/atomic mass: 236.26858

Melting point (°C):

189-193

CAS №: 298-46-4

Solubility (g/100 g of solvent):

methylene chloride: 11.9 (25°C) [Ref.]
water: 0.011 (20°C) [Ref.]

LD50 (mg/kg):

1957 (rats, oral)
529 (mice, oral)
5620 (dogs, oral)

References:

  1. Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 428-429
  2. Jouyban A. Handbook of solubility data for pharmaceutacals. – CRC Press, 2010. - pp. 70
  3. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 338-339
  4. Yalkowsky S.H., Yan H. Handbook of aqueous solubility data. - CRC Press, 2003. - pp. 997
  5. Машковский М.Д. Лекарственные средства. - 13-е изд., Т. 1. - Харьков: Торсинг, 1997. - pp. 37-38 [Russian]
  6. Токсикологический вестник. - 2003. - №3. - pp. 24-28 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru