Main page (Russian) Search in database (English)

Properties of substance:

metronidazole



skc-file

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C6H9N3O3

Structural formula as text:

CH3C3HN2(NO2)CH2CH2OH

Molar/atomic mass: 171.155

Melting point (°C):

159-163

CAS №: 443-48-1

Solubility (g/100 g of solvent):

ethanol: difficulty soluble [Ref.]
water: 0.949 (20°C) [Ref.]
water: 1.127 (30°C) [Ref.]

LD50 (mg/kg):

3000 (rats, oral)
3800 (mice, oral)

References:

  1. Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 780-781
  2. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 1318
  3. Yalkowsky S.H., Yan H. Handbook of aqueous solubility data. - CRC Press, 2003. - pp. 282-283
  4. Вартанян Р.С. Синтез основных лекарственных средств. - М.: МИА, 2004. - pp. 790-791 [Russian]
  5. Машковский М.Д. Лекарственные средства. - 13-е изд., Т. 2. - Харьков: Торсинг, 1997. - pp. 372 [Russian]

    What information do you need?




    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru