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Properties of substance:

buprenorphine hydrochloride



skc-file

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C29H42ClNO4

Molar/atomic mass: 504.1

CAS №: 53152-21-9

Solubility (g/100 g of solvent):

ethanol: soluble [Ref.]
water: difficulty soluble [Ref.]

LD50 (mg/kg):

62 (rats, intravenous)
800 (mice, oral)
72 (mice, intravenous)
79 (dogs, intravenous)

References:

  1. Buschmann H., Christoph T., Friderichs E., Maul C., Sundermann B. Analgesics from Chemistry and Pharmacology to Clinical Application. - 2002. - pp. 174
  2. Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 412
  3. Lewis R.J. Sax's Dangerous Properties of Industrial Materials. - 12ed., Vol. 1-5. - Wiley, 2012. - pp. 718
  4. Problems of Drug Dependence 1991: Proceeding of the 53rd Annual Scientific Meeting The Committee on Problems of Drug Dependence, 1992. - pp. 273
  5. Бабаян Э.А., Гаевский А.В., Бардин Е.В. Правовые аспекты оборота наркотических, психотропных, сильнодействующих, ядовитых веществ и прекурсоров. - М.: МЦФЭР, 2000. - pp. 145 [Russian]
  6. Машковский М.Д. Лекарственные средства. - 13-е изд., Т. 1. - Харьков: Торсинг, 1997. - pp. 152 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru