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Properties of substance:
2-[[3-(trifluoromethyl)phenyl]amino]benzoic acid
Synonyms:
flufenamic acid
Group of substances:
organic
Physical appearance:
needles crystals
Empirical formula (Hill's system for organic substances):
C
1
4
H
1
0
F
3
NO
2
Structural formula as text:
CF3C6H4NHC6H4COOH
Molar/atomic mass: 281.23
Melting point (°C):
133.5
CAS ¹: 530-78-9
Solubility (g/100 g of solvent):
1-octanol
: 18.07 (20°C) [
Ref.
]
1-octanol
: 21.88 (25°C) [
Ref.
]
1-octanol
: 24.8 (30°C) [
Ref.
]
1-octanol
: 37.8 (42°C) [
Ref.
]
dimethylsulfoxide
: soluble [
Ref.
]
hexane
: 0.0000047 (20°C) [
Ref.
]
hexane
: 0.0000085 (30°C) [
Ref.
]
hexane
: 0.000017 (42°C) [
Ref.
]
LD
50
(mg/kg):
715 (mice, oral)
References:
CRC Handbook of Chemistry and Physics. - 95ed. - CRC Press, 2014. - pp. 3-528
Jouyban A. Handbook of solubility data for pharmaceutacals. – CRC Press, 2010. - pp. 83, 158
The Merck Index 11th ed., Merck & Company, 1989. - pp. 646
Âàðòàíÿí Ð.Ñ. Ñèíòåç îñíîâíûõ ëåêàðñòâåííûõ ñðåäñòâ. - Ì.: ÌÈÀ, 2004. - pp. 67-68 [Russian]
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© Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru